By Jennie R. Lill,Wendy Sandoval
The definitive advisor to the myriad analytical strategies to be had to scientists keen on biotherapeutics research
Analytical Characterization of Biotherapeutics covers all present and rising analytical instruments and strategies used for the characterization of healing proteins and antigen reagents. From simple recombinant antigen and antibody characterization, to complicated analyses for more and more advanced molecular designs, the publication explores the historical past of the research strategies and provides necessary insights into an important rising analytical strategies. additionally, it frames serious questions warranting consciousness within the layout and supply of a healing protein, exposes analytical demanding situations which may take place whilst characterizing those molecules, and provides a few proven suggestions.
The first single-volume consultant of its style, Analytical Characterization of Biotherapeutics brings jointly contributions from scientists on the cutting edge of biotherapeutics study and production. Key issues lined in-depth contain the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or different hybrid molecules, characterization of producing host-cell contaminant proteins, analytical instruments for biologics molecular evaluate, and more.
- Each bankruptcy is written by means of a famous specialist or specialists of their box who talk about present and leading edge methods to totally characterizing biotherapeutic proteins and antigen reagents
- Covers the whole diversity of characterization techniques for big molecule established therapeutics
- Provides an updated account of the newest ways used for giant molecule characterization
- Chapters disguise the history had to comprehend the demanding situations to hand, recommendations to signify those huge molecules, and a precis of rising concepts for analytical characterization
Analytical Characterization of Biotherapeutics is an updated source for analytical scientists, biologists, and mass spectrometrists eager about the research of biomolecules, in addition to scientists hired within the prescription drugs and biotechnology industries. Graduate scholars in biology and analytical technological know-how, and their teachers will locate it to be attention-grabbing and instructive supplementary reading.